The Technology
What Rennou is
Rennou is a patented combination of theobromine, from cacao, paired with a calcium and phosphate system. It takes the remineralization your body already performs and supercharges it.
The finding came out of the LSU School of Dentistry, where Dr. Tetsuo Nakamoto was studying caffeine and noticed its close cousin doing the reverse: enamel growing back stronger. Twenty years of work and the patents followed. Theodent holds them.
Rennou is in every Theodent product, and in nothing else.
How it works
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Acid from food and drink draws mineral out of enamel. This happens to everyone, every day.
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Your body repairs that loss naturally, through saliva.
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Rennou supercharges the repair. Larger crystals, harder for acid to dissolve.
Not fluoride. Not nano-hydroxyapatite.
Fluoride
Adds fluoride ion to the enamel surface. It works, and it has worked for a century.
It is also a poison: every tube sold in the United States carries a federally required Poison Control warning.
Nano-hydroxyapatite
A saturation strategy: inert synthetic particles at enormous concentration, in the hope that some dissolve where they land.
Expensive, and apart from doing nothing, the least potent route to remineralization.
Rennou
Supercharges the remineralization your body already performs. At or above the level of fluoride, with none of the toxicity.
Patented, and in no other toothpaste.
The evidence
What the study found
It took 71× more fluoride to reach the remineralization theobromine achieved.
Theodent reached near-complete tubule occlusion in 3 days, and complete coverage in seven, brushing twice daily.
Fluoride achieved no meaningful occlusion of exposed tubules.
Amenchi B.T., Porteous N., Ramalingam K., Mensinkai P.K., Ccahuana-Vasquez R.A., Sadeghpour A., Nakamoto T. Remineralization of artificial enamel lesions by theobromine. Caries Research 47: 399–405, 2013. Peer-reviewed; presented at the ADA Annual Session and covered by Medscape.
Your body already repairs enamel. Rennou supercharges it.
Sources
Amenchi B.T., Porteous N., Ramalingam K., Mensinkai P.K., Ccahuana-Vasquez R.A., Sadeghpour A., Nakamoto T. Remineralization of artificial enamel lesions by theobromine. Caries Research 47: 399–405, 2013.
Poison Control warning on fluoride dentifrice. 21 CFR 355.50, U.S. Food and Drug Administration.
Zero D.T. Dentifrices, mouthwashes, and remineralization / caries arrestment strategies. BMC Oral Health 6 (Suppl 1): S9, 2006.