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Fluoride-Free Toothpaste Powered by Cacao

Theodent® replaces fluoride with Rennou®, a patented active ingredient powered by a compound found in cacao.

Shop Theodent®

Which tube is right for you?

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Theodent Classic spearmint carton among spearmint leaves and flowering stems

Classic

The daily tube for adults. Rennou® at everyday strength, for brushing morning and night.

Shop Classic
Theodent Kids chocolate chip carton among cacao pods, cacao flowers and vanilla beans

Kids

The same Rennou®, in a gentle formulation made for children.

Shop Kids
Theodent 300 Diamond Mint canister among mint leaves, citrus peel and star anise

300

Extra strength: the highest concentration of Rennou® we make.

Shop 300

fluoride-free.

powered by Rennou®.

rapid enamel remineralization.

not harmful if accidentally swallowed.

endorsed by dentists worldwide.

the first viable alternative to fluoride.

featured in The New York Times and Forbes.

Red Dot Award winner.

Theodent 300 Diamond Mint canister and tube with gold toothbrush on slate

Why cacao instead of fluoride?

Most toothpaste uses fluoride. Theodent® uses Rennou®, a patented active ingredient whose key compound comes from cacao, the fruit that is better known for what it becomes: chocolate. Rennou® is not harmful if accidentally swallowed, and in a randomized, double-blind study, its key compound remineralized enamel at concentrations 71 times lower than fluoride (Caries Research, 2013).

How Rennou® works
Theodent Classic Spearmint tube and box with gold toothbrush

Clinically proven

Read the peer-reviewed research that demonstrates the safety and efficacy of Rennou® when compared directly to fluoride.

Review the clinical evidence

Every ingredient earns its place

Rennou® gets the attention, but the same care goes into everything around it. Every Theodent® formula is built to be as clean as possible. Read about every ingredient and its purpose in our formulas.

See the ingredients

Rennou® vs. fluoride and nano-hydroxyapatite

Feature
Fluoride
Nano-hydroxyapatite
Promotes enamel remineralization
Yes
Yes
Yes
Requires a Poison Control warning?
No
Yes
No
Mechanism of action
Uses cacao to supercharge your existing remineralization process
Alters enamel chemistry to increase acid resistance
Relies on high concentrations of synthetic mineral to promote remineralization
Concentration efficacy
Comparable remineralization at 71× lower concentration than fluoride¹
Effective at low concentrations
Only effective at very high concentrations due to its relatively inert nature
Patented exclusive technology
Yes
No
No
Promotes enamel remineralization
Rennou® Yes
Fluoride Yes
nHA Yes
Requires a Poison Control warning?
Rennou® No
Fluoride Yes
nHA No
Mechanism of action
Rennou® Uses cacao to supercharge your existing remineralization processFluoride Alters enamel chemistry to increase acid resistancenHA Relies on high concentrations of synthetic mineral to promote remineralization
Concentration efficacy
Rennou® Comparable remineralization at 71× lower concentration than fluoride¹Fluoride Effective at low concentrationsnHA Only effective at very high concentrations due to its relatively inert nature
Patented exclusive technology
Rennou® Yes
Fluoride No
nHA No

¹ Amaechi et al., Caries Research 47:399–405, 2013 (randomized, double-blind).

Blog posts

Crimson cacao pods on a branch, painted from nature by Berthe Hoola van Nooten, chromolithograph, circa 1880
Cacao

Food of the Gods: The 289-Year-Old Name Behind Your Toothpaste

How an 18th-century botanist's name for the cacao tree, Theobroma (“food of the gods”), leads straight to the theobromine behind our Rennou® toothpaste.

Mainstream Science Catches Up to Long-Standing Fluoride Concerns

Mainstream Science Catches Up to Long-Standing Fluoride Concerns

Recent findings from the National Toxicology Program are bringing long-standing concerns about fluoride into the mainstream. This groundbreaking study reveals a potential link between higher fluori...

Theodent Partners with Lovell to Serve Those Who've Served Us

Theodent Partners with Lovell to Serve Those Who've Served Us

Theodent's partnership with Lovell Government Contracting Agency marks a pivotal moment in veterans' oral health care. Now listed on national contracts, our fluoride-free, Rennou™-powered toothpast...

Proudly Fluoride Free
SLS Free
Made in USA
Recyclable
Vegan
Gluten Free